HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Terry H Landowski Selected Research

4- imino- 1,3- diazabicyclo(3.1.0)hexan- 2- one

6/2016Magnetic Resonance Imaging Identifies Differential Response to Pro-Oxidant Chemotherapy in a Xenograft Model.
8/2014Phase 2 study of imexon, a prooxidant molecule, in relapsed and refractory B-cell non-Hodgkin lymphoma.
4/2012Anti-tumor activity and mechanism of action for a cyanoaziridine-derivative, AMP423.
3/2012Imexon induces an oxidative endoplasmic reticulum stress response in pancreatic cancer cells.
1/2011Imexon enhances gemcitabine cytotoxicity by inhibition of ribonucleotide reductase.
2/2009Inhibition of protein synthesis by imexon reduces HIF-1alpha expression in normoxic and hypoxic pancreatic cancer cells.
5/2007Imexon-based combination chemotherapy in A375 human melanoma and RPMI 8226 human myeloma cell lines.
1/2006Correlates of imexon sensitivity in human multiple myeloma cell lines.
1/2005Induction of apoptosis and cell cycle arrest by imexon in human pancreatic cancer cell lines.
11/2002Imexon activates an intrinsic apoptosis pathway in RPMI8226 myeloma cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Terry H Landowski Research Topics

Disease

16Neoplasms (Cancer)
06/2016 - 03/2002
8Multiple Myeloma
12/2013 - 11/2002
7Pancreatic Neoplasms (Pancreatic Cancer)
01/2020 - 01/2005
3Necrosis
06/2013 - 01/2006
2Neoplasm Metastasis (Metastasis)
06/2014 - 04/2003
2Prostatic Neoplasms (Prostate Cancer)
12/2013 - 06/2007
1Neutropenia
01/2020
1Adenocarcinoma
01/2020
1Ascites
01/2020
1Hypercapnia
06/2016
1Hyperoxia
06/2016
1Hypersensitivity (Allergy)
01/2015
1Non-Hodgkin Lymphoma (Lymphosarcoma)
08/2014
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2013
1Colonic Neoplasms (Colon Cancer)
06/2013
1B-Cell Lymphoma (Lymphoma, B Cell)
04/2012
1Hypoxia (Hypoxemia)
02/2009
1Melanoma (Melanoma, Malignant)
05/2007
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/2002
1Genetic Translocation (Chromosomal Translocation)
12/2002

Drug/Important Bio-Agent (IBA)

104- imino- 1,3- diazabicyclo(3.1.0)hexan- 2- oneIBA
06/2016 - 11/2002
4Reactive Oxygen Species (Oxygen Radicals)IBA
06/2016 - 02/2009
4Antineoplastic Agents (Antineoplastics)IBA
12/2013 - 11/2002
4Proteins (Proteins, Gene)FDA Link
04/2012 - 03/2002
3GemcitabineFDA Link
01/2020 - 01/2011
3Sulfhydryl Compounds (Thiols)IBA
06/2016 - 01/2005
3Bortezomib (Velcade)FDA Link
06/2013 - 05/2005
3Pharmaceutical PreparationsIBA
02/2008 - 10/2003
2Proteasome InhibitorsIBA
05/2007 - 05/2005
2OligonucleotidesIBA
05/2005 - 04/2003
1Cytidine DeaminaseIBA
01/2020
1folfirinoxIBA
01/2020
1TetrahydrouridineIBA
01/2020
1130-nm albumin-bound paclitaxelIBA
01/2020
1DecitabineFDA Link
01/2020
1MethyltransferasesIBA
01/2020
1DNA (Deoxyribonucleic Acid)IBA
01/2020
1Biomarkers (Surrogate Marker)IBA
06/2016
1Contrast MediaIBA
06/2016
1HeterochromatinIBA
01/2015
1Histone Deacetylases (Histone Deacetylase)IBA
01/2015
1Histone Deacetylase InhibitorsIBA
01/2015
1IntegrinsIBA
06/2014
1Laminin (Merosin)IBA
06/2014
1OxazolesIBA
12/2013
15- (4- methoxyphenyl)- 2- (3- (3- methoxyphenyl)pyridin- 4- yl)oxazoleIBA
12/2013
1TubulinIBA
12/2013
13-((4-benzylpiperazino)methyl)-1H-indoleIBA
06/2013
1Nelfinavir (Viracept)FDA Link
06/2013
1HIV Protease InhibitorsIBA
06/2013
1CaspasesIBA
06/2013
1CalpainIBA
06/2013
1AMP423IBA
04/2012
1Glutathione (Reduced Glutathione)IBA
03/2012
1Peptide Initiation Factors (Initiation Factor)IBA
03/2012
1Drug CombinationsIBA
01/2011
1Oxygen (Dioxygen)IBA
02/2009
19-(dimethylaminoethoxy)ellipticineIBA
03/2008
1ellipticineIBA
03/2008
1quinone (benzoquinone)IBA
06/2007
12- (2'- (dimethylamino)ethyl)- 1,2- dihydro- 7- ethoxydibenz(de,h)isoquinoline- 1,3- dioneIBA
06/2007
1Mitoxantrone (Novantrone)FDA LinkGeneric
06/2007
1PoisonsIBA
06/2007
1Type II DNA Topoisomerases (Topoisomerase II)IBA
06/2007
1anthraceneIBA
06/2007
1hydroquinone (Esoterica)FDA Link
06/2007
1thiazolyl blueIBA
05/2007
1lissamine rhodamine B (sulforhodamine B)IBA
05/2007
1Dexamethasone (Maxidex)FDA LinkGeneric
05/2007
1Biological ProductsIBA
01/2006
1FITC-annexin A5IBA
01/2006
1Boronic AcidsIBA
05/2005
1ATP dependent 26S protease (26S proteasome)IBA
05/2005
1Oxidants (Oxidizing Agents)IBA
01/2005
1hydroxyethyl methacrylate (HEMA)IBA
10/2003
1Fibronectins (Fibronectin)IBA
04/2003
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
12/2002
17-hydroxystaurosporine (UCN 01)IBA
11/2002
1EnzymesIBA
03/2002

Therapy/Procedure

5Therapeutics
01/2020 - 02/2008
1Injections
06/2014
1Combination Drug Therapy (Combination Chemotherapy)
05/2007
1Drug Therapy (Chemotherapy)
04/2003